testosterone deficiency syndrome

- Erectile dysfunction as an indicator
German men are still not sufficiently informed about the ways of her body and make too little to their own health. A fact that was recently confirmed as part of the First German Men's Health Men's Health Report of the Foundation and the German Agency for Health and husband again. In particular, the 40th beyond the Age occurring hormonal changes, the so-called Ageing Male' symptoms are discussed in urological practice remains low.

Professor Hermann M. Behre, Hall points to the leading clinical symptoms of testosterone deficiency in hypogonadism: Sexual dysfunction in the form of erectile dysfunction (ED) and reduced morning erections and sexual desire (libido) occur especially in men over 40 years on . "Even with a testosterone hormone serum level of 8.5 nmol / l occurs significantly more often to treat erectile dysfunction," said Behre. A determination of testosterone levels in serum is therefore recommended in the clinical diagnosis of erectile dysfunction. Why is the concept of rational treatment of erectile dysfunction or loss of libido in patients with a testosterone hormones deficiency is not taking PDE-5 inhibitors, but the testosterone replacement therapy. Patients with erectile dysfunction who respond to therapy with PDE-5 inhibitors alone and do not have the same testosterone deficiency will benefit from additional treatment with testosterone.

When testosterone replacement is displayed?

Generally, at values below 8 nmol / l after two indexes measuring the serum testosterone levels, testosterone replacement. At the limit of 8 nmol / L to 12 nmol / l treatment is needed if symptoms are present. Therapeutic doses of testosterone alone can achieve in half of patients with erectile dysfunction, a clinical benefit.According to Professor Aksam A. Yassin, Norderstedt, have shown that testosterone gel Testim ® is that it can be compared with other gel formulations higher testosterone levels in the blood, that is achieve better effects without increased side effect profile. The good tolerability, low cost and easy application form (a 5 g tube daily is equivalent to 50 mg of testosterone), provide additional patient benefits.

Genetic basis of male testosterone levels

Scientists at the Metabolic Center of Greifswald, Institute of Clinical Chemistry and Laboratory Medicine have identified together with researchers from Europe and the USA, several gene variants that affect the male testosterone levels for life. As the American science journal "PLoS GENETICS" reports in its latest edition *, it managed to show the international scientific consortium that genetic factors are responsible for a decreased testosterone hormones concentration in blood.

Testosterone is the dominant sex hormone in men and plays a central role in the development of male sexual characteristics, the Muscle and bone metabolism.Between men of similar age, however, can observe significant differences in testosterone levels for which there is currently no conclusive explanation.

Scientists at the Metabolic Center of Greifswald, Institute of Clinical Chemistry and Laboratory Medicine and the Interfaculty Institute for Genetics and Functional Genomics jointly an international research consortium has formed to investigate the genetic regulation of male testosterone levels scientifically. Out of ten research institutes from seven countries are involved. Served as the basis of the study data and blood samples of the current study population Greifswald since 1997 "Health in Pomerania" SHIP (Study of Health in Pomerania) with more than 2,000 male subjects.

By evaluating the data collected from more than 14,000 men were able for the first time previously unknown genetic factors have been identified that have an influence on the regulation of male testosterone levels. The detected genetic effects on the hormone concentration in the blood could in future lead to a more differentiated diagnosis or medical treatment of testosterone hormone deficiency. "This is a significant advance to elucidate the causes of individual differences in male hormones testosterone levels and a further important step towards a personalized medicine," informed the Greifswald endocrinologist Prof. Dr. Henri Wallaschofski.

Hormones can help brokers win

Exchange traders can expect, according to a new study just then with good profits in the stock market, if their state of the male sex hormone testosterone is very high.

Increases in hormone levels, waving in the stock market gains

A strong thrust of the sex hormone testosterone could help brokers, according to British researchers to make greater profits. In contrast, the hormone cortisol is rather with uncertainty, pain and poor performance associated according to the trading floor, said researchers at the University of Cambridge in the "Proceedings" of the U.S. Academy of Sciences.

The scientists analyzed saliva from 17 London financial traders in eight days, each morning and evening to celebrate the amount of the hormones testosterone and cortisol. These were then compared with the respective financial results of days of stock market men. It noted that Professors John Coates and Joe Herbert, that stockbrokers earned with high morning testosterone levels are often more money than others. One reason could be to conjecture of Coates and Herbert, that the more successful traders felt the testosterone by a higher self-confidence and an associated higher risk. This could influence their buying and selling decisions in stock trading therefore indirectly.

"Our work suggests that their decisions by emotional and hormonal factors have influenced that have not yet been examined closely enough," said Herbert. "Any theory for decision making in the highly demanding environment of the financial trade should in future take into account the factor of hormonal changes."

human hormones

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